A vicious serial killer is on the loose in Seattle, roaming strip clubs and gay hang-outs, believing he is on a mission to cleanse the plague infested city from sin in preparation for the apocalypse. Simultaneously, renowned FBI profiler Frank Black retires to Seattle with his family as he gains membership in the secretive Millennium Group. He soon realizes that he must be the one to bring closure to the so-called Frenchman's grotesque crimes, before further innocents are brutally killed.
When large quantities of human ashes are discovered in the flowerbeds of a San Francisco park, Frank Black joins an investigation that will lead to an overpowering cult that kills those members unwilling to conform to expectations. In getting closer to the cult's all-powerful leader, Frank gets his first glimpse of a dark force that is controlling the killers he seeks.
A man preys on seemingly random women, making his bloody mark on a world he feels has reduced him to nothing but a number. Investigating on behalf of the Millennium Group, Frank Black finds difficulty on the case in the form of Jim Horn, a partner who is ill-suited to handle the intense horrors the case represents.
A desperate man embarks on a cross-country killing spree, taking his revenge on the holy men he perceives to have led him astray in faith. Frank Black knows that the man's sense of faith, or lack thereof, is the key to stopping his killing spree. Soon, however, Frank's determination leads him right into the lion's den when he willingly walks into a hostage situation at a small town church.
A man who calls himself the Judge is the mastermind behind a number of bizarre murders involving dismemberment, leading aimless young men to kill those he commands must die. His purpose is the meting out of personal justice and his primary interests come to lie in the unique drive and talent of Frank Black
A mad bomber terrorizes Washington DC in the hopes of becoming a glorified hero, bombing buildings before then rushing in to save the victims. Frank Black joins a specialized FBI team to help catch the madman whose attention-starved personality may be the key to his undoing.
A juvenile delinquent begins taking advantage of families grieving the loss of a loved one with the support of a sadistic friend to a murderous end. Frank Black puts himself in the troubled boy's frame of mind to find answers as Catherine looks elsewhere, into the boy's tortured family life.
Catherine Black desperately tries to help a woman who was sexually abused by her father, Joe Bangs, when the man threatens to do the same to her little girl. The struggle for justice proves to be a difficult one, however, as the community reputation and political connections of Bangs remain intact despite Catherine's efforts.
Frank Black and the Seattle Police Department try to solve the mystery inherent to the murder of a couple whose young daughter was forced to witness the event, committed by a killer who uses highly protected real estate open houses as his access to victims. Catherine encourages Jordan to reach out to the young girl to help her recover from the horror she's experienced, purposely blocking the work of Bob Bletcher, who is determined to make the girl relive the incident in order to gain vital evidence.
Young men are being abducted from a specially designed private community and made to pay for the hidden sins of their fathers. Frank Black and Peter Watts try desperately to determine the killer's identity but meet an unexpected obstacle when they find the fathers simply aren't willing to admit to their crimes.
Frank Black and Peter Watts, tracing a trail of clues and bodies across both Missouri and Arkansas, must track down an emotionally distraught young woman and her murderous boyfriend before they find the baby her father sold to a childless couple.
Frank Black and Millennium Group sex crime expert Maureen Murphy are called to Colorado to investigate when a man's marriage failings turn into deadly sexual fantasies, attending local raves and swingers parties to track the killer. Unfortunately, the investigative pair finds resistance in the form of a biased sheriff and a local law enforcement team unprepared to deal with such sexual attacks.
An unusual man prepares his bizarre family of cloned daughters for the great apocalyptic disaster of May 5th, 2000. While attempting to investigate a seemingly paranormal chain of events linked to these blonde-haired, blue-eyed girls, Frank Black and the Millennium Group find they have a thorn in the side in Dennis Hoffman, a man who is a self-proclaimed expert on the great planetary alignment that will cause the anticipated disaster.
Frank Black's memories of a prominent serial killing case from his past become intensely vivid as he prepares to interview a murderer he locked away decades ago in order to catch that man's protégé, a copycat killer. Frank's concerns torture him day and night, giving him bizarre nightmares and a conscience which insists he should have killed the original killer when he was given the opportunity.
A police search strikes the Black family personally as Frank's sister-in-law, Helen, is kidnapped from her child's baptism. Frank's younger brother, Tom, finds the situation overwhelmingly difficult to deal with emotionally and foolishly chooses to take desperate measures. At home, Jordan exhibits extraordinary concern over the detailed events of the crime despite the fact that she was never present to witness them.
Frank Black wakes up in an alley amnesiac, having no idea why he attended a bizarre new drug trial, what happened to him thee, who the mysterious doctor pulling the strings is, or why he has the disturbing feeling that someone has died.
Frank Black is asked by a persistent prosecuting attorney to come to a Utah court and testify against a man on trial for confessing to the murder of his own family. Determined to weigh the evidence of the crime for himself, Frank soon finds that he doesn't believe the man he is to speak against truly committed the crime to which he's confessed.
When a psychopathic doctor once captured by Frank Black escapes his hospital bed after surgery, the famed profiler is called to Washington DC to aid in his recapture. As Frank and Peter Watts uncover clues regarding the escape they're introduced to Lucy Butler, a mysterious and dangerous woman who indicates that dark forces have specific targets that are close to Frank's home and that evil itself has plans for Frank's life.
Despite the fact that Frank feels he is unable to continue with his work on an emotional level, Peter Watts insists that he investigate a series of strange satanic slayings that may hold an unexpected link to the mysterious death of Bob Bletcher. While working on the case, the Millennium Group becomes caught in a battle between the human representations of demons and angels here on earth.
Frank Black realizes that a dangerous situation is forming when a psycho-sexual killer who has spent months slaughtering horses across North Dakota begins to gain the courage to focus his attentions on human victims.
Frank Black and Peter Watts investigate a series of brutal killings in the Brighton Beach Russian community of New York City, killings that are linked to the nuclear disaster at Chernobyl. The shotgun slayings seem to be the work of mysterious Russian diplomat Sergei Stepanovich, a man recognized by the local immigrants as Yaponchik, a mythical Russian figure destined by prophecy to be revealed as the Antichrist.
The Black family travels to visit Catherine's parents in Maryland, leading Frank to reconsider an old local case that may have been resolved improperly the first time around. The murder in question may have in fact been committed by the Woodsman, a serial killer still depositing bodies in the Maryland woods. In investigating these events, Frank might inadvertently be pulling his family closer toward the intentions of the Polaroid stalker.